Genomic insights into familial adenomatous polyposis: unraveling a rare case with whole APC gene deletion and intellectual disability

Abstract A young patient diagnosed with advanced colon cancer and liver metastasis was found to have familial adenomatous polyposis (FAP) through comprehensive genomic analysis.Whole-genome array Saddle Carriers comparative genomic hybridization (aCGH) revealed germline deletions at chromosome 5q22.1-22.2 encompassing the entire APC gene.The patien

read more




Utilizing a Personal Smartphone Custom App to Assess the Patient Health Questionnaire-9 (PHQ-9) Depressive Symptoms in Patients With Major Depressive Disorder

BackgroundAccurate reporting of patient symptoms is critical for diagnosis and therapeutic monitoring in psychiatry.Smartphones offer an accessible, low-cost means to collect patient symptoms in real time and aid in care.ObjectiveTo investigate adherence among psychiatric outpatients diagnosed with major depressive disorder in utilizing their perso

read more